Review



anti cd70 antibody  (Bio X Cell)


Bioz Verified Symbol Bio X Cell is a verified supplier
Bioz Manufacturer Symbol Bio X Cell manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 93
      Buy from Supplier

    Structured Review

    Bio X Cell anti cd70 antibody
    (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of <t>CD70+</t> cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .
    Anti Cd70 Antibody, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 93/100, based on 34 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti cd70 antibody/product/Bio X Cell
    Average 93 stars, based on 34 article reviews
    anti cd70 antibody - by Bioz Stars, 2026-05
    93/100 stars

    Images

    1) Product Images from "Transient immune landscape remodelling shapes CD8 T-cell priming during infection"

    Article Title: Transient immune landscape remodelling shapes CD8 T-cell priming during infection

    Journal: bioRxiv

    doi: 10.64898/2026.03.18.712682

    (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of CD70+ cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .
    Figure Legend Snippet: (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of CD70+ cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .

    Techniques Used: Staining, Infection, Flow Cytometry

    (A-B) Representative image of spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), XCR1 (cyan), NKp46 (red) and SIRPa ( A , magenta), or 33D1 ( B , magenta). C- Mice were adoptively transferred with OTIxGFP cells and infected with LM-OVA. Representative image of spleen sections stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green) 24hrs post-infection. (D-E) Splenocytes from mice infected with LM-OVA for 24hrs were analysed by flow cytometry. D- Representative gating strategy for splenic cDC1 and cDC2 subsets. E- Representative histograms showing CD80, CD86, and CD70 expression in cDC1 and cDC2.
    Figure Legend Snippet: (A-B) Representative image of spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), XCR1 (cyan), NKp46 (red) and SIRPa ( A , magenta), or 33D1 ( B , magenta). C- Mice were adoptively transferred with OTIxGFP cells and infected with LM-OVA. Representative image of spleen sections stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green) 24hrs post-infection. (D-E) Splenocytes from mice infected with LM-OVA for 24hrs were analysed by flow cytometry. D- Representative gating strategy for splenic cDC1 and cDC2 subsets. E- Representative histograms showing CD80, CD86, and CD70 expression in cDC1 and cDC2.

    Techniques Used: Infection, Staining, Flow Cytometry, Expressing



    Similar Products

    anti cd70 pe  (Miltenyi Biotec)
    93
    Miltenyi Biotec anti cd70 pe
    Anti Cd70 Pe, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti cd70 pe/product/Miltenyi Biotec
    Average 93 stars, based on 1 article reviews
    anti cd70 pe - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    anti cd70 antibody  (Bio X Cell)
    93
    Bio X Cell anti cd70 antibody
    (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of <t>CD70+</t> cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .
    Anti Cd70 Antibody, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti cd70 antibody/product/Bio X Cell
    Average 93 stars, based on 1 article reviews
    anti cd70 antibody - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    medium  (Miltenyi Biotec)
    93
    Miltenyi Biotec medium
    (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of <t>CD70+</t> cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .
    Medium, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/medium/product/Miltenyi Biotec
    Average 93 stars, based on 1 article reviews
    medium - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    stemmacs ips brew xf medium  (Miltenyi Biotec)
    93
    Miltenyi Biotec stemmacs ips brew xf medium
    (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of <t>CD70+</t> cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .
    Stemmacs Ips Brew Xf Medium, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/stemmacs ips brew xf medium/product/Miltenyi Biotec
    Average 93 stars, based on 1 article reviews
    stemmacs ips brew xf medium - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    xf medium  (Miltenyi Biotec)
    93
    Miltenyi Biotec xf medium
    (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of <t>CD70+</t> cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .
    Xf Medium, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/xf medium/product/Miltenyi Biotec
    Average 93 stars, based on 1 article reviews
    xf medium - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    anti cd70  (Cell Signaling Technology Inc)
    93
    Cell Signaling Technology Inc anti cd70
    (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of <t>CD70+</t> cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .
    Anti Cd70, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti cd70/product/Cell Signaling Technology Inc
    Average 93 stars, based on 1 article reviews
    anti cd70 - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    anti human cd70 apc vio 770  (Miltenyi Biotec)
    93
    Miltenyi Biotec anti human cd70 apc vio 770
    (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of <t>CD70+</t> cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .
    Anti Human Cd70 Apc Vio 770, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti human cd70 apc vio 770/product/Miltenyi Biotec
    Average 93 stars, based on 1 article reviews
    anti human cd70 apc vio 770 - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    fr70  (Bio X Cell)
    93
    Bio X Cell fr70
    (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of <t>CD70+</t> cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .
    Fr70, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/fr70/product/Bio X Cell
    Average 93 stars, based on 1 article reviews
    fr70 - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of CD70+ cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .

    Journal: bioRxiv

    Article Title: Transient immune landscape remodelling shapes CD8 T-cell priming during infection

    doi: 10.64898/2026.03.18.712682

    Figure Lengend Snippet: (A-B) Graphs show XCR1 (A) and SIRPa (B) signal density within innate-infiltrated and non-infiltrated regions on stained spleen sections harvested 24hrs after LM-OVA infection (n=5). C- Mice were adoptively transferred with OTIxGFP T-cells and infected with LM-OVA. After 24hrs, spleen sections were stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green). Representative image. (D-F) Mice were infected with LM-OVA for 24hrs and splenocytes were analysed by flow cytometry. Graphs show CD80 MFI ( D , n=5-7), CD86 MFI ( E , n=5-7), and frequency of CD70+ cDC1 and cDC2 ( F , n=4-5). (G-H) Spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), CD70 (red), CD11b (white). G- Representative image. H- Graph shows CD70 signal intensity within innate-infiltrated and non-infiltrated regions in WPs (n=5). I-K Mice were infected with LM-OVA and treated with anti-CXCR3 or anti-CD70 antibodies as indicated 6hrs before infection. Graphs show frequencies (I) , absolute numbers (J) and avidity (K) of N4-tetramer+ CD8 T-cells 8 days post-infection (n=12-17 per group). Ratio paired t-tests (A-B, D-F, H) , Welch and Brown-Forsythe one-way ANOVA with Dunnett’s multiple comparisons test (I-K) .

    Article Snippet: For CD70 blockade, mice were intraperitoneally administered 300μg anti-CD70 antibody (BioXCell, BE0022) or isotype control antibody (BioXcell, BE0290) 6hr before infection, either alone or in combination with CXCR3 blockade.

    Techniques: Staining, Infection, Flow Cytometry

    (A-B) Representative image of spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), XCR1 (cyan), NKp46 (red) and SIRPa ( A , magenta), or 33D1 ( B , magenta). C- Mice were adoptively transferred with OTIxGFP cells and infected with LM-OVA. Representative image of spleen sections stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green) 24hrs post-infection. (D-E) Splenocytes from mice infected with LM-OVA for 24hrs were analysed by flow cytometry. D- Representative gating strategy for splenic cDC1 and cDC2 subsets. E- Representative histograms showing CD80, CD86, and CD70 expression in cDC1 and cDC2.

    Journal: bioRxiv

    Article Title: Transient immune landscape remodelling shapes CD8 T-cell priming during infection

    doi: 10.64898/2026.03.18.712682

    Figure Lengend Snippet: (A-B) Representative image of spleen sections from mice infected with LM-OVA for 24hrs were stained for CD169 (blue), XCR1 (cyan), NKp46 (red) and SIRPa ( A , magenta), or 33D1 ( B , magenta). C- Mice were adoptively transferred with OTIxGFP cells and infected with LM-OVA. Representative image of spleen sections stained for CD169 (red), 33D1 (magenta), XCR1 (cyan), OTI (green) 24hrs post-infection. (D-E) Splenocytes from mice infected with LM-OVA for 24hrs were analysed by flow cytometry. D- Representative gating strategy for splenic cDC1 and cDC2 subsets. E- Representative histograms showing CD80, CD86, and CD70 expression in cDC1 and cDC2.

    Article Snippet: For CD70 blockade, mice were intraperitoneally administered 300μg anti-CD70 antibody (BioXCell, BE0022) or isotype control antibody (BioXcell, BE0290) 6hr before infection, either alone or in combination with CXCR3 blockade.

    Techniques: Infection, Staining, Flow Cytometry, Expressing